Fast Five Quiz: Presentation and Diagnosis of Hereditary (Familial) Amyloid Transthyretin-Related (hATTR) Amyloidosis

Jefferson R. Roberts, MD

Disclosures

July 11, 2019

hATTR is staged according to the patient's walking disability and degree of assistance required. There are four stages, 0 to III, as disease severity worsens. Stage 0 indicates patients are asymptomatic carriers of a known TTR mutation. In stage I, patients show signs of sensory polyneuropathy. Walking capacity is preserved without needing the assistance of a cane. In stage II, patients exhibit progressive walking disability; they are still ambulatory but require the assistance of one or two canes or crutches. Patients with stage III hATTR are wheelchair bound or bedridden.

Learn more about staging hATTR.

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