Fast Five Quiz: Common Skin Conditions

William James, MD


May 20, 2019

A brief summary and highlights of the AAAAI guidelines:

  • Second-generation nonsedating H1 antihistamines are indicated as first-line treatment.

  • First-generation H1 antihistamines remain in the treatment algorithm (differs from some other guidelines).

  • Equally weighted second-line options to consider include updosing second-generation H1 antihistamines; adding other second-generation H1 antihistamines; and adding H2 antagonists, leukotriene receptor antagonists, or first-generation H1 antihistamines at bedtime.

  • Omalizumab is a third-line treatment option.

  • Corticosteroids are considered only for short-term intervention; they should be avoided as long-term treatment.

  • Cyclosporine A may be used as an add-on for refractory chronic urticaria not responsive to other treatments.

Read more about urticaria.


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