Clinical manifestations of PAH may include the following:
History of heart murmur
Deep venous thrombosis or pulmonary embolism
Raynaud phenomenon
Arthritis or arthralgias
Rash
Heavy alcohol consumption
Hepatitis
Heavy snoring
Daytime hypersomnolence
Morning headaches
Morbid obesity
Family history of pulmonary hypertension
Drug use, in particularly diet drugs and illicit drugs
Medications
Patients with PAH may also have nonspecific symptoms secondary to pulmonary hypertension. These may include the following:
Dyspnea on exertion
Fatigue
Lethargy
Syncope with exertion
Chest pain
Anorexia
Right upper quadrant pain
Less common symptoms include the following:
Cough
Hemoptysis
Hoarseness (resulting from compression of the recurrent laryngeal nerve by the distended pulmonary artery)
The intensity of the pulmonic component of the P2 may be increased, and the P2 may demonstrate fixed or paradoxical splitting. A systolic ejection murmur may be heard over the left sternal border. The murmur may be augmented by inspiration. A right ventricular heave may be palpated.
Although PAH has been associated with thyroid dysfunction, the most common association is with hyperthyroidism.
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Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Zab Mosenifar. Fast Five Quiz: Pulmonary Arterial Hypertension - Medscape - Jun 14, 2019.
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