Fast Five Quiz: Pulmonary Arterial Hypertension

Zab Mosenifar, MD

Disclosures

June 14, 2019

According to Guidelines for Diagnosis and Treatment of Pulmonary Hypertension from the American College of Cardiology, high-risk (>10% 1-year mortality) features include the following:

  • Clinical signs of right heart failure

  • Rapid progression

  • Repeated syncope

  • World Health Organization functional class (WHO FC) IV

  • 6-minute walk distance <165 m

  • B-type natriuretic peptide level of 300 ng/L

  • Pericardial effusion

  • Right atrial pressure of >14 mm Hg

  • Cardiac index of <2 L/m/m2

  • Mixed venous oxygen saturation of <60%

Low-risk (<5% in 1-year mortality) features include the following:

  • No sign of right heart failure

  • No progression of symptoms

  • WHO FC I, II

  • 6-minute walk distance of >440 m

  • B-type natriuretic peptide level of <50 pg/L

  • No pericardial effusion

  • Normal right atrial size

  • Right atrial pressure of <8 mm Hg

  • Cardiac index of ≥2.5 L/min/m2

  • Mixed venous oxygen saturation of >65%

Read more on the diagnosis of PAH.

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