Fast Five Quiz: Pulmonary Arterial Hypertension

According to Guidelines for Diagnosis and Treatment of Pulmonary Hypertension from the American College of Cardiology, high-risk (>10% 1-year mortality) features include the following:

• Clinical signs of right heart failure

• Rapid progression

• Repeated syncope

• World Health Organization functional class (WHO FC) IV

• 6-minute walk distance <165 m

• B-type natriuretic peptide level of 300 ng/L

• Pericardial effusion

• Right atrial pressure of >14 mm Hg

• Cardiac index of <2 L/m/m²

• Mixed venous oxygen saturation of <60%

Low-risk (<5% in 1-year mortality) features include the following:

• No sign of right heart failure

• No progression of symptoms

• WHO FC I, II

• 6-minute walk distance of >440 m

• B-type natriuretic peptide level of <50 pg/L

• No pericardial effusion

• Normal right atrial size

• Right atrial pressure of <8 mm Hg

• Cardiac index of ≥2.5 L/min/m²

• Mixed venous oxygen saturation of >65%

Read more on the diagnosis of PAH.

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Cite this: Zab Mosenifar. Fast Five Quiz: Pulmonary Arterial Hypertension - Medscape - Jun 14, 2019.