Fast Five Quiz: Presentation and Diagnosis of Systemic Sclerosis

Dirk M. Elston, MD


October 09, 2019

The level of C-reactive protein, a marker of inflammation, was determined to be above normal in approximately 1 in 4 patients with SSc. This finding was particularly common in early disease, where it correlated with disease activity, severity, poor pulmonary function, and shorter survival.

Fibrosis of the basal parts of the lungs is observed in approximately 30%-60% of patients.

Anti-PM/Scl antibodies are seen in 3%-10% of patients with SSc.

Approximately 12% of SSc-related deaths result from pulmonary hypertension.

To learn more about laboratory, imaging, and other tests in SSC, click here


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