Fast Five Quiz: Autism Spectrum Disorder

Stephen Soreff, MD


July 05, 2019

Electroencephalography is useful for ruling out seizure disorder, acquired aphasia with convulsive disorder (Landau-Kleffner syndrome), biotin-responsive infantile encephalopathy, and related conditions in children with suspected ASD. Although universal screening is not recommended, it should be considered for children who demonstrate clear language regression and those with clinical signs that might represent seizures.

No clinical evidence currently supports the role of routine clinical neuroimaging in the diagnostic evaluation of autism. Studies of various imaging techniques have yielded inconsistent results, and although characteristic abnormalities have been identified, no single finding is diagnostic.

Several metabolic abnormalities have been identified in investigations of people with ASD. However, biological markers for ASD are not yet identified. No blood studies are recommended for the routine assessment of children with ASD.

Psychophysiologic assessment is indicated in children with autism. Children are not likely to show the response habituation in respiratory period, electrodermal activity, and vasoconstrictive peripheral pulse amplitude response to repeatedly presented stimuli seen in typical children. Children with autism may also demonstrate auditory overselectivity.

Read more about the workup of ASD.


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