Fast Five Quiz: Bleeding Disorders

Emmanuel C. Besa, MD

Disclosures

July 11, 2019

The most common signs of von Willebrand disease include nosebleeds and hematomas. Prolonged bleeding from trivial wounds, oral cavity bleeding, and excessive menstrual bleeding are common. Gastrointestinal bleeding rarely occurs. Other manifestations include the following:

  • Easy bruising – common but nonspecific

  • Prolonged bleeding – after minor trauma to skin or mucous membranes

  • Severe hemorrhage – after major surgery; a less common sign

  • Delayed bleeding – may occur up to several weeks after surgery

  • Heavy bleeding – common after tooth extraction or other oral surgery, such as tonsillectomy and adenoidectomy

  • Menorrhagia – common presenting complaint in women

  • Exacerbation of bleeding symptoms – after ingestion of aspirin

  • Amelioration of bleeding symptoms with use of oral contraceptives

Men and women are equally affected by von Willebrand disease. However, the phenotype may be more pronounced in women due to menorrhagia and the greater visibility of bruises.

Read more about von Willebrand disease.

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