The Case Challenge series includes difficult-to-diagnose conditions, some of which are not frequently encountered by most clinicians but are nonetheless important to accurately recognize. Test your diagnostic and treatment skills using the following patient scenario and corresponding questions. If you have a case that you would like to suggest for a future Case Challenge, please contact us.
A 67-year-old man who was diagnosed with Parkinson disease 8 years ago has experienced recent, unintentional weight loss. He lost 30 lb over the course of 12 months. He is 6'1" tall and his weight is now 136 lb (61.7 kg), giving him a body mass index of 18 kg/m2, which is slightly underweight.
The patient has never been overweight. His cholesterol and blood glucose levels were previously in the upper limits of the reference range. However, he has not recently been dieting or trying to lose weight. He states that he has not paid much attention to how much he has been eating lately.
Other than Parkinson disease, the patient does not have a significant or relevant medical history. He has been taking a combination of amantadine and carbidopa/levodopa, with good control of his motor symptoms. His Parkinson disease is mainly characterized by a resting tremor in his left arm; muscle rigidity in all four extremities; a flat affect; and a slow, shuffling gait.
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Cite this: Heidi Moawad. Dramatic Weight Loss in a Patient With Parkinson Disease - Medscape - Jul 25, 2019.