Unlike patients with RRMS whose symptoms improve or resolve between episodes occurring months or years apart, patients with SPMS start to exhibit progressive neurologic change over time. Patient may exhibit relapses but often do not recover, and MRIs may still show the accrual of lesions.
Resolving paresthesia in patients diagnosed with MS is indicative of RRMS.
Cognitive dysfunction that resolves with rest is not a symptom of MS.
The EDSS is a tool used to describe the severity of disability in patients with MS. An EDSS score of 1 indicates minimal disability and would not pertain to a patient who has SPMS.
Learn more about the clinical presentation of SPMS.
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Cite this: Krupa Pandey. Fast Five Quiz: Secondary Progressive Multiple Sclerosis - Medscape - Feb 16, 2021.