Fast Five Quiz: Antibiotic Best Practices

Mary L. Windle, PharmD


September 11, 2019

Recent guidelines from NICE state that for patients with C trachomatis infection, the first-line agent is doxycycline. Azithromycin is the second-line choice and is preferred in pregnant or breastfeeding women or in patients with an allergy or intolerance to doxycycline.

According to guidelines from NICE, prompt antibiotic therapy is recommended in patients with scarlet fever; penicillin VK is recommended as initial treatment, with clarithromycin indicated if a penicillin allergy is present.

NICE does not recommend the use of antibiotics in patients with sinusitis symptoms lasting ≤ 10 days. In patients with symptoms lasting > 10 days with no improvement, antibiotic use depends on the likelihood of bacterial sinusitis.

According to NICE guidelines, preferred antibiotics for acute prostatitis include ciprofloxacin, ofloxacin, or trimethoprim. Second-line agents include levofloxacin or cotrimoxazole.

Read more about the treatment of chlamydia.


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