The specific Diagnostic and Statistical Manual of Mental Disorders, fifth edition, criteria for major depressive disorder are outlined below.
At least five of the following symptoms have to have been present during the same 2-week period (and at least one of the symptoms must be diminished interest/pleasure or depressed mood):
Depressed mood: for children and adolescents, this can also be an irritable mood
Diminished interest or loss of pleasure in almost all activities (anhedonia)
Significant weight change or appetite disturbance: for children, this can be failure to achieve expected weight gain
Sleep disturbance (insomnia or hypersomnia)
Psychomotor agitation or retardation
Fatigue or loss of energy
Feelings of worthlessness
Diminished ability to think or concentrate; indecisiveness
Recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt or specific plan for committing suicide
The symptoms must cause significant distress or impairment in social, occupational, or other important areas of functioning. The symptoms must not be attributable to the physiologic effects of a substance (eg, a drug of abuse, a medication) or another medical condition. The disturbance must not be better explained by a persistent schizoaffective disorder, schizophrenia, delusional disorder, or other specified or unspecified schizophrenia spectrum and other psychotic disorders. No manic episodes or hypomanic episodes can have been reported.
Depressive disorders can be rated as mild, moderate, or severe. The disorder can also occur with psychotic symptoms, which can be mood congruent or incongruent. Depressive disorders can be determined to be in full or partial remission.
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Cite this: George D. Harris. Fast Five Quiz: Stress-Related Conditions - Medscape - Sep 26, 2019.