Fast Five Quiz: Bladder Cancer Presentation and Diagnosis

Kyle A. Richards, MD


December 29, 2020

The UICC/AJCC TNM staging system, which is used to stage bladder cancers, classifies tumors that have invaded the lamina propria as T1.

The TNM staging system for bladder cancer is as follows:

  • CIS: Carcinoma in situ, high-grade dysplasia, confined to the epithelium

  • Ta: Papillary tumor confined to the epithelium

  • T1: Tumor invasion into the lamina propria

  • T2: Tumor invasion into the muscularis propria

  • T3: Tumor involvement of the perivesical fat

  • T4: Tumor involvement of adjacent organs, such as the prostate, rectum, or pelvic sidewall

  • N+: Lymph node metastasis

  • M+: Metastasis

Rather than grouping bladder tumors as superficial (T1 and below) and invasive (T2 and above), urologic oncologists now recommend avoiding the term "superficial bladder cancer." This term groups patients who may require different treatments and who may have different prognoses.

Learn more about the staging of bladder cancer.


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