Clinical depression, also referred to as major depressive disorder (MDD), is an extremely disabling, multifaceted psychiatric illness. Highly prevalent, it affects more than 300 million individuals worldwide. MDD involves symptoms (which can be recurring) of both affect and cognition. Cognitive impairment is among the most frequent enduring symptoms of MDD. MDD is also associated with short- and long-term functional impairments that affect mood and motivation; patients frequently experience significantly reduced quality of life and psychosocial functioning as well as physical health problems. MDD is a significant contributor to suicide and, on rare occasions, homicide.
It has been estimated that 70% of patients do not achieve remission following first-line antidepressant medication, and that full functional recovery may be compromised even after achieving symptomatic remission.
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Cite this: Stephen Soreff. Fast Five Quiz: Depression and Cognition - Medscape - Dec 31, 2019.