The most common gastrointestinal site of metastatic spread in lung cancer is the liver. The most common sites of distant metastases in the body also include bone, the adrenal glands and intra-abdominal lymph nodes, the brain and spinal cord, and the lymph nodes and skin.
Approximately one third of patients with lung cancer have symptoms as a result of distant metastases. Paraneoplastic syndromes occur more frequently in patients with SCLC than in those with NSCLC.
Cardiac findings related to NSCLC metastases are usually noted when the tumor causes a pericardial effusion. The findings may range from simple effusion to tamponade; direct cardiac involvement may also arise.
Learn more about the symptoms of distant metastases in NSCLC.
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Cite this: Daniel S. Schwartz. Fast Five Quiz: Non–Small Cell Lung Cancer - Medscape - Feb 03, 2021.