Fast Five Quiz: Advanced and Metastatic Prostate Cancer Presentation and Diagnosis

Daniel S. Schwartz, MD, MBA

June 27, 2022

In patients with advanced or metastatic prostate cancer, physical examination findings may include adenopathy; other findings in patients with advanced disease may include cancer cachexia, lower extremity lymphedema or deep venous thrombosis, bony tenderness, and over-distended bladder due to outlet obstruction.

Low-grade prostate cancers can be biologically active. In high-grade prostate cancer, the percentage of Gleason grades 4 and 5 disease present is associated with adverse pathologic findings and disease progression.

Obliteration of the lateral sulcus found during rectal examination frequently indicates locally advanced disease, as does seminal vesical involvement.

Learn more about the presentation of advanced and metastatic prostate cancer.

1 2 3 4 5 6

Next Section

Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.

Cite this: Daniel S. Schwartz. Fast Five Quiz: Advanced and Metastatic Prostate Cancer Presentation and Diagnosis - Medscape - Jun 27, 2022.

Comments

Commenting is limited to medical professionals. To comment please Log-in.

Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.