Fast Five Quiz: Chronic Lymphocytic Leukemia (CLL) Presentation and Diagnosis

Karl J. D'Silva, MD

Disclosures

March 17, 2020

Figure 1. Blood smear showing chronic lymphocytic leukemia

CLL is diagnosed when there is evidence of the disease in both the blood and bone marrow. Unlike small lymphocytic lymphoma (SLL), which is another manifestation of the same disease, CLL is diagnosed when > 5000 monoclonal lymphocytes/µL are present for > 3 months. The bone marrow is either normocellular or hypercellular, with > 30% monoclonal lymphocytes.

Learn more about diagnostic criteria of CLL.

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