Fast Five Quiz: Chronic Lymphocytic Leukemia (CLL) Presentation and Diagnosis

Karl J. D'Silva, MD


March 08, 2022

Expression of CD20 is dim in CLL, whereas it is bright in mantle cell lymphoma. Another feature that can help in differentiating the two conditions is that mantle cell lymphoma expresses CD5 and CD19, but not CD23 antigen — something that is expressed in CLL. In addition, mantle cell lymphoma usually expresses FMC-7.

Learn more about the differential diagnosis of CLL.


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