Fast Five Quiz: Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

Karl J. D'Silva, MD


June 23, 2020

Figure 1. CLL in bone marrow

Relapsed CLL is defined as evidence of disease progression ≥ 6 months after an initial complete response or partial response. Complete response means that many parameters have been met, including lymph node size < 1.5 cm, spleen size < 13 cm, normal liver size, normal constitutional symptoms, and normal circulating lymphocyte count. Partial response includes such parameters as a decrease of ≥ 50% from baseline in the size of lymph nodes, liver, or spleen size, and an increase of ≥ 50% over baseline in circulating lymphocyte count.

Learn more about diagnosing CLL.


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