CLL transforms into large B-cell lymphoma (also known as Richter syndrome) in up to 10% of patients. Viral infections, especially those common in immunosuppressed patients (eg, Epstein-Barr virus), are thought to prompt this transition. CLL can transform into other aggressive disease, including Hodgkin lymphoma and rare interdigitating dendritic cell sarcoma.
Learn more about CLL transformation.
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Cite this: Karl J. D'Silva. Fast Five Quiz: Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) - Medscape - Jun 23, 2020.
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