Fast Five Quiz: Cholangiocarcinoma Presentation and Diagnosis

N. Joseph Espat, MD, MS


February 20, 2020

Thailand has the highest annual incidence of cholangiocarcinoma, at 85 cases per 100,000 people in the northeastern part of the country, and 5.7 cases per 100,000 people in the southern part of the country. Although there are a few other outliers, including Chile, Bolivia, and South Korea, where the incidence is high, in most places where the incidence rate is known, cholangiocarcinoma is a rare cancer (defined by an incidence of less than six cases per 100,000 people). This includes Australia (0.43 cases per 100,000 people), the United States (1.6 cases per 100,000 people), and Italy (3.36 cases per 100,000 people).

Reports suggest the incidence of intrahepatic cholangiocarcinoma is on the rise, whereas the incidence of extrahepatic cholangiocarcinoma is declining.

Learn more about the incidence of cholangiocarcinoma.


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