According to IDSA/ATS guidelines, at least one major criterion or three minor criteria define the presence of severe CAP. Minor criteria include the following:
Respiratory rate ≥ 30 breaths/minute
PaO2/FiO2 ratio ≤ 250
Uremia (BUN level ≥ 20 mg/dL)
Leukopenia (white blood cell count < 4000 cells/μL)
Thrombocytopenia (platelet count < 100,000/μL)
Hypothermia (core temperature < 36°C)
Hypotension requiring aggressive fluid resuscitation
Major criteria include septic shock with the need for vasopressors and respiratory failure requiring mechanical ventilation.
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Cite this: Michael Stuart Bronze. Fast Five Quiz: Pneumonia Key Aspects - Medscape - Mar 23, 2020.