Fast Five Quiz: Psoriatic Arthritis Presentation and Diagnosis

Herbert S. Diamond, MD; Eric M. Ruderman, MD; Marina Magrey, MD


January 25, 2023

Recognizing the patterns of joint involvement seen in psoriatic arthritis is essential to its diagnosis.

PsA is accompanied by both peripheral and axial manifestations of musculoskeletal disease. Peripheral joint diseases include polyarticular, oligoarticular, distal, and arthritis mutilans subtypes. Asymmetrical oligoarticular arthritis, with or without spine involvement, is one of the most common subtypes of PsA, particularly in the early disease state; many patients progress to more symmetrical polyarticular disease.

  • Spondylitis with or without sacroiliitis

Ocular complications are common in patients with PsA. Approximately one third (31%) of patients with PsA develop ocular complications, including notably high incidence rates of acute anterior uveitis. Uveitis is usually bilateral, unlike in ankylosing spondylitis where it is unilateral, with an alternating pattern. Scleritis and keratoconjunctivitis sicca may occur, but they are usually rare.

Learn more about the physical examination of patients with psoriatic arthritis.


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