Fast Five Quiz: Atopic Dermatitis

Richard P. Vinson, MD; William James, MD


February 09, 2023

Incessant pruritus is not only the most common presenting symptom of AD, but according to the American Academy of Dermatology Guideline, it is an essential feature of AD required for the diagnosis. In addition to pruritus, another essential feature of AD is a chronic or relapsing history of eczematous lesions. Additional features of AD might include early age of onset, personal or family history of allergy, immunoglobulin (Ig) E reactivity, and xerosis.

Dennie-Morgan folds (lines), infraorbital folds in the skin below the lower eyelid, are one of the minor criteria for AD.

The dirty neck sign, associated with chronic AD, is a brown, macular ring that develops around the neck and is caused by post-inflammatory hyperpigmentation and frictional melanosis.

Pus-filled blisters associated with AD result from secondary Staphylococcus aureus infection.

Learn more about the clinical presentation of AD.


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