Fast Five Quiz: Nasal Polyps

Arlen D. Meyers, MD, MBA


February 06, 2020

Monoclonal antibodies may be an effective treatment for nasal polyps. In a randomized, double-blind, placebo-controlled, parallel-group study, the addition of subcutaneous dupilumab to mometasone furoate nasal spray reduced the endoscopic nasal polyp burden in patients with nasal polyposis refractory to intranasal corticosteroids.

Intranasal steroid sprays may decrease or slow the growth of small nasal polyps, but they are relatively ineffective in massive nasal polyposis. Use of intranasal steroid sprays may be helpful after nasal polypectomy to help prevent recurrence.

Oral corticosteroids are regarded as the most effective medical treatment for nasal polyps. They have been shown to quickly and substantially reduce the size of inflammatory polyps and improve symptoms.

Antifungal agents have no role in the management of nasal polyposis, but these agents may be useful in cases of allergic fungal sinusitis with polyposis.

Learn more about the management of nasal polyps.


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