Monoclonal antibodies may be an effective treatment for nasal polyps. In a randomized, double-blind, placebo-controlled, parallel-group study, the addition of subcutaneous dupilumab to mometasone furoate nasal spray reduced the endoscopic nasal polyp burden in patients with nasal polyposis refractory to intranasal corticosteroids.
Intranasal steroid sprays may decrease or slow the growth of small nasal polyps, but they are relatively ineffective in massive nasal polyposis. Use of intranasal steroid sprays may be helpful after nasal polypectomy to help prevent recurrence.
Oral corticosteroids are regarded as the most effective medical treatment for nasal polyps. They have been shown to quickly and substantially reduce the size of inflammatory polyps and improve symptoms.
Antifungal agents have no role in the management of nasal polyposis, but these agents may be useful in cases of allergic fungal sinusitis with polyposis.
Learn more about the management of nasal polyps.
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Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Arlen D. Meyers. Fast Five Quiz: Nasal Polyps - Medscape - Feb 06, 2020.
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