Fast Five Quiz: Plaque Psoriasis

William James, MD


June 09, 2021

Like other systemic agents, biologic therapies may be considered for patients with severe and refractory plaque psoriasis. Biologics may also be considered for patients with active psoriatic arthritis.

Phototherapy should only be initiated in patients with extensive, widespread disease (ie, more lesions than can easily be counted). Patients who are resistant to topical treatment may also be candidates for phototherapy.

Combination topical/systemic therapy appears to yield better outcomes than either treatment used alone for the treatment of plaque psoriasis.

Outpatient topical therapy is still considered the first-line treatment of plaque psoriasis. Various topical treatments are available (eg, corticosteroids, coal tar, anthralin, calcipotriene, tazarotene).

For additional information, refer to the British Association of Dermatologists guidelines for biologic therapy for psoriasis (2017) and the Joint AAD–NPF Guidelines of care for the management and treatment of psoriasis with topical therapy and alternative medicine modalities for psoriasis severity measures.

Learn more about treatment options for plaque psoriasis.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as: