Each year worldwide, as many as 300,000 patients are diagnosed with sickle cell disease (SCD). SCD is most common among patients whose ancestors came from sub-Saharan Africa and Southeast Asia. SCD is a life-threatening hematologic disorder in which there is a disruption of blood flow in small vessels; this vaso-occlusion leads to distal tissue ischemia and inflammation. Repeated episodes of sickling and ongoing hemolytic anemia, even when subclinical, culminate in parenchymal injury and chronic organ damage. Although the disease course is highly variable, significant morbidity and early mortality often ensue. Early diagnosis is key to improving survival.
How much do you know about the presentation and diagnosis of SCD? Test your knowledge with this quick quiz.
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Cite this: Sophie M. Lanzkron. Fast Five Quiz: Sickle Cell Disease Presentation and Diagnosis - Medscape - Sep 24, 2021.