Each year worldwide, as many as 400,000 individuals are born with sickle cell disease (SCD). SCD is a life-threatening hematologic disorder in which abnormal sickle-shaped erythrocytes disrupt blood flow in small vessels; this vaso-occlusion leads to distal tissue ischemia and inflammation. Repeated episodes of sickling and ongoing hemolytic anemia, even when subclinical, culminate in parenchymal injury and chronic organ damage. Although the disease course is highly variable, significant morbidity and early mortality often ensue. Early diagnosis is key to improving survival.
How much do you know about the presentation and diagnosis of SCD? Test yourself with this quick quiz.
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Cite this: Sophie M. Lanzkron. Fast Five Quiz: Sickle Cell Disease Presentation and Diagnosis - Medscape - Apr 07, 2020.
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