ACE inhibitors, which may be prescribed in heart failure, have been shown to lead to a higher risk for anemia in patients with heart failure.
Hemodilution is also considered to play a role in the development of anemia in heart failure; other potential etiologies include the renin-angiotensin-aldosterone system, inflammatory cytokines, and renal dysfunction.
Nutritional deficiencies, such as iron deficiency, are among the most important factors that lead to anemia in heart failure. Inadequate erythropoietin production resulting from renal failure, intrinsic bone marrow defects, and medication use may also play a significant role in the development of anemia.
Iron deficiency is highly prevalent in patients with heart failure, affecting about 50% of patients.
Learn more about the management of patients with heart failure and anemia.
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Cite this: Arnold S. Baas, Jeff Hsu. Fast Five Quiz: Iron Deficiency and Anemia in Heart Failure - Medscape - Mar 15, 2021.
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