Fast Five Quiz: Squamous Cell Non-Small Cell Lung Cancer

Maurie Markman, MD


May 05, 2021

Lung cancer continues to be the leading cause of cancer-related deaths worldwide. Non–small cell lung cancer (NSCLC), which accounts for 85% of all lung cancers, is divided histologically into adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. In the United States, Canada, and many European countries, squamous cell carcinoma is the second most common histologic subtype of lung cancer; in other countries, such as Spain and the Netherlands, it remains the most common. Squamous pearl formation, keratin production, and intercellular bridging are characteristic of squamous cell tumors. A complete staging workup is required to assess the extent of disease and determine the choice of treatment. Regardless of subtype, diagnosis is not usually made until there is a poor prognosis due to advanced disease. Earlier diagnosis, though rare due to a lack of symptoms, allows for improved treatment outcomes.

How much do you know about squamous cell NSCLC? Test your knowledge with this quick quiz.


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