Fast Five Quiz: Fungal Infection Management

Michael Stuart Bronze, MD


April 17, 2020

Fluconazole or oral nystatin suspension is the treatment of choice for thrush, and several other antifungal agents are also effective.

For older children and adults, antifungal medications should be swished around in the oral cavity and swallowed. Failure to do so may provide ineffective treatment for lesions in the posterior pharynx and esophagus. In younger patients, apply 1-2 mL of the solution to the inside of each cheek.

Resistance to nystatin is rare, although the drug's contact killing makes it somewhat more difficult to use because it must be applied to all of the affected mucosal surfaces to be effective.

The best time to administer medication is between meals, because this allows longer contact time.

Learn more about the management of thrush.


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