Fast Five Quiz: Huntington Disease

Shaheen E. Lakhan, MD, PhD, MS, MEd

Disclosures

May 27, 2020

The initial stages of Huntington disease are often characterized by deficits in short-term memory. This is frequently followed by motor dysfunction and a variety of cognitive changes, including diminished verbal fluency and problems with attention, executive function, visuospatial processing, and abstract reasoning.

As the disease progresses, chorea coexists with and is then gradually replaced by dystonia and parkinsonian features, including bradykinesia, rigidity, and postural instability.

Akinetic-rigid syndrome occurs in advanced disease with minimal or no chorea.

Although the dementia syndrome associated with Huntington disease includes early-onset behavioral changes such as irritability, untidiness, and loss of interest, the slowing of cognition and impairment of intellectual function, along with memory disturbances, are seen as the disease progresses.

Learn more about the clinical presentation of Huntington disease.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....