Fast Five Quiz: Huntington Disease

Shaheen E. Lakhan, MD, PhD, MS, MEd

Disclosures

May 27, 2020

While there is no cure for Huntington disease, for those patients experiencing symptoms, various medications can improve the quality of life and prevent complications. Treatments for Huntington disease can be divided into drugs to treat the movement disorder and drugs to treat psychiatric or behavioral problems.

Benzodiazepines should be considered in patients with chorea that is severe enough to interfere with function. Other treatment options for chorea include valproic acid, dopamine-depleting agents (eg, reserpine, tetrabenazine deutetrabenazine), and neuroleptics.

Neuroleptics may worsen other features of the disease, such as bradykinesia and rigidity, leading to further functional decline. Patients with predominant features of bradykinesia and rigidity may benefit from treatment with levodopa or dopamine agonists.

Ablative surgical procedures and fetal cell transplantation have been attempted in Huntington disease patients, but there are not enough data to support this type of treatment and it is still considered experimental.

Learn more about the treatment of Huntington disease.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....