Fast Five Quiz: Huntington Disease

Shaheen E. Lakhan, MD, PhD, MS, MEd


May 27, 2020

SSRIs are considered first-line treatment for depression in patients with Huntington disease. Bupropion, venlafaxine, nefazodone, and tricyclic antidepressants can also be prescribed. Electroconvulsive therapy may be used in patients with refractory depression. It is important to note that depression in this patient population is treatable and should be recognized and treated promptly.

For patients with hallucinations, delusions, or schizophrenia-like syndromes, newer antipsychotic agents are preferred to older agents because of the lower incidence of extrapyramidal side effects and the decreased risk for tardive syndromes.

Learn more about the treatment of depression in Huntington disease.


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