Initiation of saccadic movements is slow and uncoordinated, and smooth pursuit is interrupted by saccadic intrusions. Patients are unable to inhibit saccades toward a peripheral stimulus when instructed to look in the opposite direction.
Eye movement abnormalities can be seen early in the disease.
The clinical signs of Huntington disease change during the course of the illness; different patterns may be observed, depending on the age of onset.
While chorea is the most common movement disorder seen at the time of symptom onset, it is gradually replaced by dystonia and parkinsonian features as the disease progresses and is less prominent in the advanced stages of the illness.
Learn more about the physical characteristics of Huntington disease.
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Cite this: Shaheen E. Lakhan. Fast Five Quiz: Huntington Disease Signs and Symptoms - Medscape - May 27, 2020.