Fast Five Quiz: Anemia in Myelodysplastic Syndrome

Emmanuel C. Besa, MD


May 12, 2021

Patients with iron overload may experience cardiac complications such as congestive heart failure. Dyspnea, orthopnea, paroxysmal nocturnal dyspnea, and lower extremity swelling should alert the clinician to the possibility of iron overload–induced heart failure.

Mucous membrane pallor is a likely consequence of iron deficiency, not iron overload. Patients with iron overload may experience a change in skin color to bronze or gray. Visual disturbances and diarrhea are more likely to occur as complications of iron chelation therapy rather than from an underlying iron overload.

Learn more about the clinical presentation of iron overload. 


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