Fast Five Quiz: Rheumatoid Arthritis Workup

Herbert S. Diamond, MD


June 10, 2020

Figure 1. Arthritis of the index finger.

According to the 2010 ACR/EULAR classification criteria, synovitis of at least one of the patient's joints must be present to establish a diagnosis of "definite RA," along with the following:

  1. Absence of an alternative diagnosis that better explains the synovitis

  2. A total assessment score of ≥ 6 points, summed from these 4 domains (factors):

    1. Number and site of involved joints

    2. Serologic abnormality

    3. Elevated acute-phase response

    4. Symptom duration

Results from laboratory evaluation, such as tests for RF, ACPA, CRP level, or ESR, can contribute to—but are not necessary for—the diagnosis of RA. Some patients with early RA may have asymmetric joint involvement, so the criteria do not require symmetric arthritis.

Learn more about the 2010 ACR/EULAR classification criteria for diagnosing RA.


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