The etiology of sepsis is diverse, and clinical clues in various organ systems aid in appropriate workup and diagnosis. Distinguishing between infectious and noninfectious causes of fever in a patient with sepsis is also important. According to a review of nearly 50 million sepsis cases, the most common underlying cause of sepsis worldwide is diarrheal disease, followed by these conditions:
Lower respiratory infections
Typhoid and paratyphoid
Chronic obstructive pulmonary disease
Chronic kidney disease
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Cite this: Richard H. Sinert. Fast Five Quiz: Sepsis Key Aspects - Medscape - Jun 17, 2020.