Ankylosing spondylitis (AS) is a chronic, multisystem inflammatory disorder primarily affecting the axial skeleton and sacroiliac joints. AS is one of the seronegative spondyloarthropathies, which are multisystem inflammatory diseases. Most of these disorders are associated with an increased incidence of human leukocyte antigen B27 (HLA-B27). AS often affects younger people in their prime working years. Diagnostic difficulties are common in AS, often leading to delayed diagnosis, which can cause long-lasting inflammation in the axial skeleton and structural damage, such as fatty lesions, erosions, and ankylosis. Physical disability can ensue, greatly impairing patients' abilities of daily activities. Effective diagnosis is key to reducing the burden associated with this disorder.
How much do you know about the signs and symptoms of ankylosing spondylitis? Test your knowledge with this quick quiz.
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Cite this: Herbert S. Diamond. Fast Five Quiz: Ankylosing Spondylitis Signs and Symptoms - Medscape - Feb 03, 2022.