Fast Five Quiz: Ankylosing Spondylitis Signs and Symptoms

Herbert S. Diamond, MD; Marina Magrey, MD


March 16, 2023

Ankylosing spondylitis (AS) is a chronic, multisystem inflammatory disorder primarily affecting the axial skeleton and sacroiliac joints. AS is one of the seronegative spondyloarthropathies, which are multisystem inflammatory diseases. Most of these disorders are associated with an increased incidence of human leukocyte antigen B27 (HLA-B27). AS often affects younger people in their prime working years. Diagnostic difficulties are common in AS, often leading to delayed diagnosis, which can cause long-lasting inflammation in the axial skeleton and structural damage, such as fatty lesions, erosions, and ankylosis. Physical disability can ensue, greatly impairing patients' abilities of daily activities. Effective diagnosis is key to reducing the burden associated with this disorder.

How much do you know about the signs and symptoms of ankylosing spondylitis? Test your knowledge with this quick quiz.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.