Peripheral musculoskeletal involvement occurs in 30%-50% of patients with AS. Peripheral arthritis predominantly involves the lower extremity joints like knees and ankles but other joints can also get involved. Enthesitis, which is inflammation at the site of insertion of ligaments and tendons onto bone, is a common clinical feature. The most frequently involved sites include:
Insertion of the plantar fascia on the calcaneus or the metatarsal heads
Achilles tendon insertion
Base of the fifth metatarsal head
Superior and inferior poles of the patella
Other sites of involvement include:
Involvement of the temporomandibular joint occurs in approximately 10% of patients and involvement of the costovertebral and costotransverse joints can occur, leading to decreased range of motion and restriction in respiration.
Learn more about the clinical presentation of AS.
Medscape © 2023 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Herbert S. Diamond, Marina Magrey. Fast Five Quiz: Ankylosing Spondylitis Signs and Symptoms - Medscape - Mar 16, 2023.