Fast Five Quiz: Ankylosing Spondylitis Management

Herbert S. Diamond, MD


June 29, 2020

The objective of corticosteroid treatment for patients with AS and uveitis is reduction of inflammation. Corticosteroids decrease the recruitment of inflammatory cells and alter cell function. They may be administered topically, via periocular injection, or systemically, and then tapered slowly.

Therapeutic levels of corticosteroids cannot be achieved in the vitreous via the topical route; therefore, this method of administration is ineffective for posterior segment disease.

Systemically administered corticosteroids may be considered for vision-threatening uveitis unresponsive to maximal topical and periocular therapy.

Learn more about the management of ophthalmologic manifestations of AS.


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