Fast Five Quiz: Alcohol Use Disorder

Stephen Soreff, MD


September 02, 2020

Alcohol biomarkers are physiologic indicators of alcohol exposure or ingestion and may reflect the presence of an alcohol use disorder. These biomarkers are not meant to be a substitute for a comprehensive history and physical examination by an appropriate health professional. Instead, alcohol biomarkers should be a complement to self-reported measures of drinking.

Indirect alcohol biomarkers suggest heavy alcohol use by detecting the toxic effects that alcohol may have had on organ systems or body chemistry. Indirect alcohol biomarkers include AST, ALT, GGT, mean corpuscular volume (MCV), and CDT. As a screen for alcohol dependence, the sensitivity and specificity of CDT is generally higher than AST, ALT, GGT, or MCV.

Read more about laboratory studies in alcohol use disorder.


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