Fast Five Quiz: Atopic Dermatitis Presentation and Diagnosis

William D. James, MD

Disclosures

September 14, 2020

Figure 1. Atopic dermatitis.

Atopic dermatitis is believed to result from a complex interplay between environmental exposures, epidermal barrier dysfunctions, and immune dysregulation. Although a single genetic risk factor has not been identified, mutations in filaggrin are thought to play a role in the pathogenesis of the disease. A deficiency in filaggrin weakens skin barrier integrity, resulting in increased epidermal permeability and susceptibility to irritant and allergic reactions.

A family history of allergic rhinitis, asthma, or atopic dermatitis increases the risk for atopic dermatitis. The disease is more prevalent in urban areas than in rural areas.

Passive tobacco smoke is considered a modest risk factor for the development of atopic dermatitis.

Learn more about atopic dermatitis.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....