Iron Deficiency Anemia Clinical Practice Guidelines (AGA, 2020)

American Gastroenterological Association (AGA)

This is a quick summary of the guidelines without analysis or commentary. For more information, go directly to the guidelines by clicking the link in the reference.

September 30, 2020

The American Gastroenterological Association (AGA) published clinical practice guidelines on iron deficiency anemia on August 15, 2020.[1,2]

The AGA recommendations for iron deficiency anemia include the following:

In patients with anemia, a cutoff of 45 ng/mL is recommended over 15 ng/mL when using ferritin to diagnose iron deficiency.

In asymptomatic postmenopausal women and men with iron deficiency anemia, bidirectional endoscopy is recommended over no endoscopy.

In asymptomatic premenopausal women with iron deficiency anemia, bidirectional endoscopy is suggested over iron replacement therapy only.

In patients with iron deficiency anemia without other identifiable etiology after bidirectional endoscopy, noninvasive testing for Helicobacter pylori, followed by treatment if positive, is suggested over no testing.

In patients with iron deficiency anemia, suggest against routine gastric biopsies to diagnose atrophic gastritis.

In asymptomatic adults with iron deficiency anemia and plausible celiac disease, initial serologic testing, followed by small bowel biopsy only if positive, is suggested over routine small bowel biopsies.

In uncomplicated asymptomatic patients with iron deficiency anemia and negative bidirectional endoscopy, a trial of initial iron supplementation is suggested over the routine use of video capsule endoscopy.

For more information, please go to Iron Deficiency Anemia.

For more Clinical Practice Guidelines, please go to Guidelines.

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