Thyroid cancer guidelines from JAES issued in 2020 recommend total thyroidectomy, prophylactic lymph node dissection, and radioactive iodine therapy for poorly differentiated carcinoma. Other recommendations include:
The management of papillary thyroid carcinoma should be based on risk classification. Total thyroidectomy is recommended for high-risk papillary thyroid carcinoma but not for very low- and low-risk PTC (T1N0M0).
Total thyroidectomy and radioactive iodine therapy are recommended for widely invasive follicular thyroid carcinoma with distant metastasis (M1). Completion total thyroidectomy is not uniformly recommended for widely invasive follicular thyroid carcinoma without distant metastasis (M0) diagnosed after lobectomy.
All patients with medullary thyroid carcinoma should undergo RET gene mutation analysis. Prophylactic total thyroidectomy is not uniformly recommended for carriers of RET mutations who have not developed medullary thyroid carcinoma.
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Cite this: Elwyn C. Cabebe, Lori J. Wirth. Fast Five Quiz: Thyroid Cancer Practice Essentials - Medscape - Sep 08, 2022.