Fast Five Quiz: Exudative (Wet) Age-Related Macular Degeneration Presentation and Diagnosis

F. Ryan Prall, MD

Disclosures

November 04, 2020

Rapid-sequence FA is performed in many patients with the signs and symptoms of exudative AMD. Abnormalities are discovered in areas where the dye accumulates (hyperfluorescence) or is absent (hypofluorescence). FA findings consistent with exudative AMD include hypofluorescent blockage from subretinal hemorrhage; increasing hyperfluorescence secondary to dye leakage from the CNV may also be seen.

Other findings that are consistent with any form of AMD include hyperfluorescence of drusen and RPE atrophy as well as hypofluorescence from RPE hypertrophy. 

A lesion that hyperfluoresces in the early phases of the angiogram, maintains well-demarcated borders, and leaks late (obscuring its borders) is consistent with a classic CNV. A lesion whose borders cannot be determined by FA is an occult CNV. 

Learn more about imaging studies in wet AMD.

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