Fast Five Quiz: Osteoporosis Hip Fracture Risk Factors

Herbert S. Diamond, MD

Disclosures

December 10, 2020

In a recently published study, community-dwelling women ≥ 80 years of age with osteoporosis were found to have a high 5-year probability of hip fracture despite accounting for competing mortality risk, suggesting that drug treatment to prevent hip fractures may be beneficial in this population. The 5-year hip fracture probability in this population was 13% even after the competing risk for mortality was accounted for. Conversely, a much lower 5-year hip fracture probability of 4% was observed among women ≥ 80 years of age without osteoporosis, even though they had been identified as high fracture risk on the basis of having osteopenia and a 10-year predicted fracture probability at or above the FRAX intervention thresholds proposed by the NOF.

A recent retrospective study found that worse general health indirectly contributed to the imminent risk for hip fractures, specifically by having a negative influence on physical functioning. Cognition also had an indirect association with imminent hip fracture risk.

The FRAX tool to evaluate fracture risk includes a parental history of hip fracture as a clinical risk factor for subsequent hip fractures in patients with osteoporosis.

Type 2 diabetes mellitus has been shown to significantly increase the risk for hip fracture.

Learn more about risk factors associated with osteoporosis.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....