Rietschel and Fowler proposed the following as primary diagnostic criteria for irritant contact dermatitis:
Macular erythema, hyperkeratosis, or fissuring predominating over vesiculation
Glazed, parched, or scalded appearance of the epidermis
Healing process beginning promptly on withdrawal of exposure to the offending agent
Negative results on patch testing that includes all possible allergens
Minor objective criteria for irritant contact dermatitis include the following:
Sharp circumscription of the dermatitis
Evidence of gravitational influence, such as a dripping effect
Lower tendency for the dermatitis to spread than in cases of allergic contact dermatitis
Morphologic changes suggesting small differences in concentration or contact time producing large differences in skin damage
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Cite this: William James. Fast Five Quiz: Dermatitis - Medscape - Nov 04, 2020.