Fast Five Quiz: Lipids Management: High HDL Cholesterol Levels (Hyperalphalipoproteinemia)

Romesh Khardori, MD, PhD

Disclosures

December 03, 2020

Apo AI and apo AII are the major apolipoproteins of HDL-C; therefore, HALP is associated with an elevated concentration of apo AI and apo AII. Apolipoprotein B (apoB) is a major component of very-low-density lipoprotein cholesterol (VLDL-C), intermediate-density lipoprotein cholesterol (IDL-C), and LDL-C. The total serum apoB level corresponds to the total number of VLDL-C, IDL-C, and LDL-C particles because they are associated with apoB molecule.

ApoE is a major cholesterol carrier. It supports lipid transport and injury repair in the brain. APOE polymorphic alleles are the main genetic determinants of Alzheimer's disease risk.

ApoF is a minor apolipoprotein that is associated with LDL-C.

Learn more about the major apolipoproteins of HDL-C.

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