Fast Five Quiz: Cardiovascular Disease Risk Management in Women

Yasmine S. Ali, MD


December 14, 2020

Updated guidelines from the ESC and EAS for the management of dyslipidemia include new, more aggressive proposed goals for LDL-C levels; revised CV risk stratification, particularly for patients at high to very high risk; and new patient management recommendations. These include the following:

  • For patients at high risk (10-year risk for CV death of 5% to < 10%): Use an LDL-C reduction of at least 50% from baseline and an LDL-C goal < 1.8 mmol/L (< 70 mg/dL).

  • For very high-risk patients who experience a second vascular event within 2 years (not necessarily of the same type as the first event) while taking maximally tolerated statin therapy: An LDL-C goal < 1.0 mmol/L (< 40 mg/dL) may be considered.

  • For individuals at moderate risk (10-year risk for CV death of 1% to < 5%): Consider an LDL-C goal < 2.6 mmol/L (< 100 mg/dL).

  • For individuals at low risk (10-year risk for CV death < 1%): Consider an LDL-C goal < 3.0 mmol/L (< 116 mg/dL).

Other recommendations include consideration of cardiovascular imaging for assessment of atherosclerotic CVD risk, such as assessment of carotid and/or femoral arterial plaque burden on arterial ultrasonography as a risk modifier in individuals at low or moderate risk. Similarly, CAC score assessment with CT can be considered as a risk modifier in the CV risk assessment of asymptomatic individuals at low or moderate risk.

Learn more about the management of CVD risk.


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