Fast Five Quiz: Multiple Sclerosis Signs and Symptoms

Christopher Luzzio, MD


January 05, 2021

About 30%–50% of MS patients experience pain during the course of their illness. In the context of MS, pain is classified as either primary or secondary. Primary pain is related to the demyelinating process itself — neuropathic pain often described as burning, gnawing, or shooting. An example of secondary MS pain is musculoskeletal discomfort caused by spasticity.

Typically, pain is not associated with a less favorable prognosis, nor does it always impair function but it can have a significant impact on quality of life. In optic neuritis, pain is often associated with eye movement.

Learn more about the signs and symptoms of MS.


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